Rief Group

Prof. Dr. Matthias Rief

Proteins are fascinating examples of self-organized molecular machines. Without any help a polypeptide strand can fold into functional threedimensional structures. We are interested in studying the function and folding process of proteins on the single molecule level. Examples are single molecule folding/unfolding studies or the motility of molecular motors in optical traps.

Latest Publications

 

M. Jahn, J. Buchner, T. Hugel and M. Rief (2016)
Folding and assembly of the large molecular machine Hsp90 studied in single-molecule experiments


K. Austen, P. Ringer, A. Mehlich, A. Chrostek-Grashoff, C. Kluger, Chr. Klingner, B. Sabass, R. Zent, M. Rief and C. Grashoff (2015)
Extracellular rigidity sensing by talin isoform-specific mechanical linkages




Research Areas

Protein Folding
Protein-Protein Interactions
Molecular Motors
Cytoskeletal Mechanics